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貝母辛

分析標(biāo)準(zhǔn)品,HPLC≥98%

Peimisine

CAS號(hào)：19773-24-1

分子式：C27H41NO3

分子量：427.62

MDL：MFCD30207851

別名：貝母新堿; 貝母辛

產(chǎn)品介紹

熔點(diǎn)：270℃

沸點(diǎn)：573℃ at 760mmHg

比旋光度：(c, 1 in CHCl3)-33.2;(c, 0.58 in EtOH)-44.6

外觀：無色結(jié)晶粉末

溶解性：溶于三氯*甲烷、乙mi、甲醇

儲(chǔ)存條件：2-8℃

注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán) 威性，僅供客戶參考交流研究之用。

參考文獻(xiàn)(22篇)

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21. [IF=8.3] Zhi-hao Wu et al."YiQiChuTan Formula (YQCTF) inhibit the progression of non-small cell lung cancer via down-regulating EGFR/ITGB2 signaling: triangulated evidence from network pharmacology, proteomic profiling, and experimental validation."PHYTOMEDICINE.2

20. [IF=5.4] Chen Le-xin et al."Yi Qi Chu Tan Formula (YQCTF) inhibited the progress of lung cancer via regulating tumor-associated neutrophil: An integrated study of network pharmacology, proteomics and pharmacodynamics."JOURNAL OF ETHNOPHARMACOLOGY.2023 Aug;:116943

19. [IF=1.698] Jinyan Wu et al."Chemical Identification and Antioxidant Screening of Bufei Yishen Formula using an Offline DPPH Ultrahigh-Performance Liquid Chromatography Q-Extractive Orbitrap MS/MS."International Journal of Analytical Chemistry.2022 Oct 15;2022:142380

18. [IF=2.586] Yue Zhao et al."An ultra-performance liquid chromatography-quadrupole time-of-flight tandem mass spectrometry method based on a four-step analysis strategy to investigate metabolites of Qi-Yu-San-Long decoction in rat plasma."RAPID COMMUNICATIONS IN MASS

17. [IF=5.988] Mengwen Huang et al."Discovering the potential active ingredients of Qi-Yu-San-Long decoction for anti-oxidation, inhibition of non-small cell lung cancer based on the spectrum-effect relationship combined with chemometric methods.."Frontiers in Pharmacol

16. [IF=4.996] Yuan Jie et al."Systematic characterization of the components and molecular mechanisms of Jinshui Huanxian granules using UPLC-Orbitrap Fusion MS integrated with network pharmacology."Scientific Reports.2022 Jul;12(1):1-24

15. [IF=4.769] Ting Zheng et al."Delineating the dynamic metabolic profile of Qi-Yu-San-Long decoction in rat urine using UPLC-QTOF-MSE coupled with a post-targeted screening strategy."Journal of Pharmaceutical Analysis. 2022 May;:

14. [IF=5.34] Dong Shao et al."Identification of the active compounds and functional mechanisms of Jinshui Huanxian formula in pulmonary fibrosis by integrating serum pharmacochemistry with network pharmacology."PHYTOMEDICINE. 2022 Jul;102:154177

13. [IF=4.411] Simona S. Ghanem et al."Natural Alkaloid Compounds as Inhibitors for Alpha-Synuclein Seeded Fibril Formation and Toxicity."Molecules. 2021 Jan;26(12):3736

12. [IF=2.882] By Feng Pan et al."Fusarium redolens 6WBY3, an endophytic fungus isolated from Fritillaria unibracteata var. wabuensis, produces peimisine and imperialine-3β-d-glucoside."Fitoterapia. 2015 Jun;103:213

11. [IF=5.34] Feng Pan et al."Peimisine and peiminine production by endophytic fungus Fusarium sp. isolated from Fritillaria unibracteata var. wabensis."Phytomedicine. 2014 Jul;21:1104

10.  Feng Pan, Kai Hou, Feng Gao, Bo Hu, Que Chen, Wei Wu, Peimisine and peiminine production by endophytic fungus Fusarium sp. isolated from Fritillaria unibracteata var. wabensis, Phytomedicine, Volume 21, Issues 8–9, 2014, Pages 1104-1109, ISSN 0944-7113, ht

9.  Pan, Feng, et al. "Fusarium redolens 6WBY3, an endophytic fungus isolated from Fritillaria unibracteata var. wabuensis, produces peimisine and imperialine-3β-d-glucoside." Fitoterapia 103 (2015): 213-221.https:##doi.org/10.1016/j.fitote.2015.04.006

8.  程斌,周愛珍,彭昕,王昕蕾,王娟.浙貝母UPLC-Q-TOF-MS/MS指紋圖譜的建立及其抗炎質(zhì)量標(biāo)志物的分析[J].中國(guó)藥房,2020,31(17):2129-2135.

7.  雨田, 練心潔, 孫佑玲,等. 浙貝母原產(chǎn)地及其遷地引種后含量分析[J]. 成都大學(xué)學(xué)報(bào)(自然科學(xué)版), 2018, 37(04):36-38+49.

6.  陳鵲, 王元彪, 劉正瓊,等. 暗紫貝母產(chǎn)生物堿內(nèi)生真菌的篩選及生物堿抑菌活性的測(cè)定[J]. 中國(guó)抗生素雜志, 2012.

5.  韓鴻萍  鄭紅  馬天一 等. 分子印跡-化學(xué)發(fā)光傳感器測(cè)定貝母屬類樣品中的貝母素乙[J]. 化學(xué)試劑  2016  038(011):1081-1085.

4.  陳鵲  王元彪  劉正瓊 等. 產(chǎn)生物堿的甘肅貝母內(nèi)生真菌的篩選 鑒定及抑菌活性測(cè)定. 中國(guó)農(nóng)學(xué)通報(bào)  2012.

3.  崔艷茹,劉海云,屈飛.貝母辛對(duì)內(nèi)毒素誘導(dǎo)小鼠急性肺損傷保護(hù)作用的研究[J].時(shí)珍國(guó)醫(yī)國(guó)藥,2014,25(09):2118-2120.

2.  崔艷茹, 劉海云, 屈飛. 貝母辛對(duì)LPS致黏液高分泌小鼠MUC5AC和EGFR表達(dá)的影響[J]. 中藥藥理與臨床, 2015(03):17-21.

1.  潘峰  侯凱  董品利 等. HPLC-ELSD法同時(shí)檢測(cè)瓦布貝母三種生物堿的含量[J]. 核農(nóng)學(xué)報(bào)  2014  28(010):1854-1859.

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